SAFE ANTIMICROBIAL AGENTS

Caprylhydroxamic Acid, pure or in a blend, as a sterilizing and antiseptic active ingredient

 The demand for hand hygienizing products has increased enormously and many companies, specialized in cosmetics or medical device, have started or are planning to start this kind of production.

We are presented with a new, never seen scenario, where hygienizing gels will play a key role in everyday life and will be used by everyone dozens of times a day. On the one hand, then, traditional aggressive products will have to be replaced by milder ones: the goal now isn’t just disinfecting in special occasions, but sistematically sanitizing hands after each and every activity while avoiding, or at least reducing, skin damage. On the other hand, we can reasonably expect a diversification in the demand of hygienizing products, as they will be needed by several different client categories: men and women, children, schools, offices, restaurants, shops, bars and so on. And some of these clients will probably be ready to spend more for this kind of products than they would do before.

Amik Italia has launched two active ingredients with optimal sterilizing and antiseptic properties, that may be added to delicate formulas of hygienizing products: SpecKare 7309 and SpecGuard GCPH.

SpecKare 7309 is pure Caprylhydroxamic Acid, an organic acid derived from coconut oil with NOI (Natural Origin Index) = 79,9%. Though gentle and natural, CHA is a powerful and versatile antimicrobial agent for mild hygienizing products.

As a kind of extremely weak organic acid, CHA has the unique characteristic of keeping in a non-ionization state in a pH range from acid to neutral, where most acid preservatives are ineffective. CHA can therefore be used in wider pH range, even in nearly neutral pH, which makes it more suitable to a mild formula than all inorganic and most organic acids, only effective in a very aggressive pH such as 3-4.

CHA works through its capacity of chelating metal ions, that affects the microorganism enzymatic and metabolic processes, combined to its carbon chain lenght (C8) that can effectively penetrate the cell membrane, unbalancing the microorganism activity. CHA is therefore an effective, performing antimicrobial agent for many different applications, but these days it could turn out to be even more interesting as a support for cleansing products, if we think that Coronavirus belongs to the category of capsule membrane/coated virus.

The second product, SpecGuard GCPH, is a blend with Caprylhydroxamic Acid and Grapefruit Seed Extract, designed as a gentle sterilizing and antiseptic agent, non toxic and non irritating, suitable for sensitive skin.

We have already listed the properties of CHA. Grapefruit Seed Extract, on the other hand, is obtained by converting grapefruit pith and pulp into a very acidic liquid, then enriched with phyto-flavonoids (polyphenolic compounds, including principally Naringin but also Quercitin, Hesperidin, Campherol Glycoside, Neohesperidin, Apigenin, Rutinoside, Poncirin, etc), powerful anti-oxidant free radical scavengers. Tests show that the reaction between the flavonoids and Ascorbic Acid creates the anti-bacterial efficacy of GSE, as its microbial uptake alters the cell membrane and inhibits enzymatic activities.

SpecGuard GCPH was tested on wet wipes and has proved its efficacy for rapid sterilization of bacteria and fungi in a 1,2% percentage of use. All the tested bacteria and most fungi are killed in 1 minute, whereas all fungi are killed in 3 minutes. Its germicidal action combined with its natural mildness makes this ingredient extremely interesting, these days more than ever.